1-(Furan-2-ylmethyl)-1H-pyrazol-3(2H)-one CAS 53409-46-4
| CAS No. | 53409-46-4 |
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Furan-2-ylmethyl)-1H-pyrazol-3(2H)-one (CAS 53409-46-4), molecular formula C8H8N2O2 and molecular weight 164.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Furan-2-ylmethyl)-1H-pyrazol-3(2H)-one (C8H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
Related Furan Standards
- Furan-2-yl(furan-3-yl)methanol (CAS 1343770-55-7)
- furan-2-yl(1H-imidazol-2-yl)methanol (CAS 1502768-59-3)
- (3-(Furan-2-yl)-1H-pyrazol-5-yl)methanol (CAS 84978-67-6)
- (3-(Furan-2-yl)isoxazol-5-yl)methanamine (CAS 27473-54-7)
- (5-(Furan-2-yl)isoxazol-3-yl)methanamine (CAS 850375-13-2)
- 3-(furan-2-yl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one (CAS 37432-58-9)
- Ethyl 3-(furan-2-yl)prop-2-ynoate (CAS 38898-09-8)
- 2-(Furan-3-yl)cyclohexan-1-one (CAS 1343456-25-6)
Recommended Standards
- 1-(Benzo[d][1,3]dioxol-4-yl)ethan-1-one (CAS 33842-14-7)
- 1-(Hydroxyimino)-1-(pyridin-2-yl)propan-2-one (CAS 65882-98-6)
- 1-(Benzo[c][1,2,5]oxadiazol-5-yl)ethanol (CAS 59660-58-1)
- 1-(Methoxymethyl)-1H-imidazo[4,5-b]pyrazine (CAS 359792-91-9)
- Methyl 3-iodo-1h-indole-5-carboxylate (CAS 1257847-81-6)
- 3-Iodo-1-methyl-1H-pyrrole-2-carboxylic acid (CAS 1823935-30-3)
- 3-(2-Chlorobenzyl)azetidine hydrochloride (CAS 1354961-30-0)
- 5-Amino-3-(4-(tert-butyl)phenyl)isoxazole-4-carbonitrile (CAS 1017668-90-4)
- 2-(2,3,6-trifluorophenyl)acetaldehyde (CAS 1256477-66-3)
- 7-Cyclopropyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 936901-93-8)
- (S)-1-Formylpyrrolidine-2-carboxamide (CAS 59867-86-6)
- Methyl 3-(4-methoxy-2-methylphenyl)benzoate (CAS 1820603-39-1)
- 4-(Difluoromethoxy)-3-nitroaniline, >98% (CAS 1261747-80-1)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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