4,4’-Difluorobenzoin CAS 53458-16-5
| CAS No. | 53458-16-5 |
| Molecular Formula | C14H10F2O2 |
| Molecular Weight | 248.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4’-Difluorobenzoin is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,4’-Difluorobenzoin (CAS 53458-16-5), a certified reference material (molecular formula C14H10F2O2, MW 248.22 g/mol) for analytical method development and quality control.
4,4’-Difluorobenzoin (C14H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10F2O2 |
| Molecular Weight | 248.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
Recommended Standards
- 4-(tert-Butoxy)-2,3,5,6-tetrafluorostyrene (CAS 343305-41-9)
- 4,4-difluoro-1-(naphthalen-1-yl)butane-1,3-dione (CAS 832739-87-4)
- 4-(Benzyloxy)-2,6-difluorobenzaldehyde (CAS 918524-93-3)
- 4,4'-Difluoro-3-Methoxybenzophenone (CAS 94108-96-0)
- (2-Chlorophenyl)(4-((2,5-dihydro-1H-pyrrol-1-yl)methyl)phenyl)methanone (CAS 898764-37-9)
- 2-AMINO-5-NITRO-4-PICOLINE 2-Amino-4-methyl-5-nitropyridine 21901-40-6 4-METHYL-5-NITRO-2-PYRIDINAMINE 4-METHYL-5-NITRO-2-PYRIDYLAMINE 4-METHYL-5-NITRO-PYRIDIN-2-YLAMINE AS04891 (CAS 21901-40-6)
- Na-(tert-Butoxycarbonyl)-1-methyl-D-tryptophan (CAS 103943-63-1)
- 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 5-bromo- (CAS 1207625-52-2)
- Acetylcysteine Impurity 12 (CAS 1115-65-7)
- Ethyl 4,4-diethoxybutanoate (CAS 4220-65-9)
- Ethyl 2-amino-4-(4-tert-butylphenyl)-5-methylthiophene-3-carboxylate (CAS 350989-72-9)
- 5-Chloro-4-(((2-chlorophenyl)thio)methyl)-1-methyl-3-((p-tolylthio)methyl)-1H-pyrazole (CAS 318248-71-4)
- Mianserin Impurity 108 (CAS CATO-C4X-1369108)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
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