9-((2R,4S,5R)-4-Chloro-5-(chloromethyl)tetrahydrofuran-2-yl)-9H-purin-6-amine CAS 53549-09-0

Purity 97%+In StockPharmaceutical Standards
CAS No.53549-09-0
Molecular FormulaC10H11Cl2N5O
Molecular Weight288.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

9-((2R,4S,5R)-4-Chloro-5-(chloromethyl)tetrahydrofuran-2-yl)-9H-purin-6-amine CAS 53549-09-0 chemical structure

Description

The occurrence of 9-((2R,4S,5R)-4-Chloro-5-(chloromethyl)tetrahydrofuran-2-yl)-9H-purin-6-amine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

9-((2R,4S,5R)-4-Chloro-5-(chloromethyl)tetrahydrofuran-2-yl)-9H-purin-6-amine (CAS 53549-09-0), molecular formula C10H11Cl2N5O and molecular weight 288.13 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 9-((2R,4S,5R)-4-Chloro-5-(chloromethyl)tetrahydrofuran-2-yl)-9H-purin-6-amine (C10H11Cl2N5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11Cl2N5O
Molecular Weight288.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms5

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