1-Hydroxy-N-pyridin-2-yl-2-naphthamide CAS 5355-36-2
| CAS No. | 5355-36-2 |
| Molecular Formula | C16H12N2O2 |
| Molecular Weight | 264.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Hydroxy-N-pyridin-2-yl-2-naphthamide (CAS 5355-36-2), a certified reference material (molecular formula C16H12N2O2, MW 264.28 g/mol) for analytical method development and quality control.
1-Hydroxy-N-pyridin-2-yl-2-naphthamide (C16H12N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12N2O2 |
| Molecular Weight | 264.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
- N-(2-Hydroxy-1,1-dimethylethyl)-3-(3-nitrophenyl)acrylamide (CAS 100098-62-2)
- Phenyl 1-hydroxy-2-naphthoate (CAS 132-54-7)
- 2-Hydroxy-5-(naphthalen-2-yl)benzoic acid (CAS 151826-05-0)
- 2-Hydroxy-5-(naphthalen-1-yl)benzoic acid (CAS 1580484-27-0)
- Methyl 4-hydroxy-1-(phenylcarbamoyl)pyrrolidine-2-carboxylate (CAS 183290-11-1)
- (2-Hydroxy-3-methylquinoxalin-6-yl)(phenyl)methanone (CAS 325469-51-0)
- (2Z)-6-Hydroxy-2-[(2E)-3-phenylprop-2-en-1-ylidene]-1-benzofuran-3(2H)-one (CAS 88281-20-3)
- 1-Hydroxy-3,5-diphenylpyrazin-2(1H)-one (CAS 33837-38-6)
Recommended Standards
- 1-Hydroxy-N-pyridin-3-yl-2-naphthamide (CAS 63210-47-9)
- 1H,1'H-[2,3'-Biindole]-2',3-diol (CAS 75038-06-1)
- 1-Phenyl-3-(pyridin-3-yl)-1h-pyrazole-4-carboxamide (CAS 882231-15-4)
- 1-Ethyl-6-(pyrazin-2-yloxy)-1H-indole-3-carbonitrile (CAS 876733-19-6)
- 2-(2-Butoxyphenyl)ethan-1-amine hydrochloride (CAS 61035-92-5)
- Diethyl 3,6-dimethylpyrazine-2,5-dicarboxylate (CAS 24691-47-2)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-methylbutanoic acid (CAS 1082544-09-9)
- 2-[(4-chloro-6-fluoroquinolin-8-yl)amino]ethan-1-ol (CAS 1803600-35-2)
- 2-(2-Chloro-2,2-difluoroacetyl)cyclohexan-1-one (CAS 2343-34-2)
- Ethyl 2-imino-1-(2-methoxyethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 371209-38-0)
- 1,3:2,4-Di-p-methylbenyliedene Sorbitol (CAS 54686-97-4)
- 2-[(4-fluorophenoxy)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 929972-42-9)
- 4-(1H-pyrrol-1-yl)piperidine hydrochloride (CAS 1803570-07-1)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com