5-(2-Chlorostyryl)-3-methyl-4-nitroisoxazole CAS 53557-98-5
| CAS No. | 53557-98-5 |
| Molecular Formula | C12H9ClN2O3 |
| Molecular Weight | 264.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Chlorostyryl)-3-methyl-4-nitroisoxazole (C12H9ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(2-Chlorostyryl)-3-methyl-4-nitroisoxazole (CAS 53557-98-5) is a high-purity analytical reference standard with the molecular formula C12H9ClN2O3 and a molecular weight of 264.66 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2-Chlorostyryl)-3-methyl-4-nitroisoxazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O3 |
| Molecular Weight | 264.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorostyryl Standards
- 5-(4-Chlorostyryl)-3-methyl-4-nitroisoxazole (CAS 53557-97-4)
- (E)-2-(2-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1355094-04-0)
- (E)-2-(3-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 871125-84-7)
- 2-(2-Chlorostyryl)-5-methyloxazole-4-carboxylic acid (CAS 89723-91-1)
- 2-(3-Chlorostyryl)-5-methyloxazole-4-carboxylic acid (CAS 89724-04-9)
- 2-(4-Chlorostyryl)-5-methyloxazole-4-carboxylic acid (CAS 89723-98-8)
- (E)-2-(4-Chlorostyryl)quinoline (CAS 38101-91-6)
- 2-(4-Chlorostyryl)-5-methylbenzo[d]oxazole (CAS 2639-35-2)
Recommended Standards
- 4-Chloro-5-(difluoromethyl)-6-morpholinopyrimidin-2-amine (CAS 2149598-74-1)
- 5-(4-Chlorobenzyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde (CAS 21328-03-0)
- 4-Amino-7-chloro-1,3-dihydrofuro[3,4-c]quinoline-8-carboxylic acid (CAS 2774613-66-8)
- 3-(4-Chlorophenoxy)-5-nitroaniline (CAS 208122-61-6)
- Antirrhinin (CAS 65941-77-7)
- N-ethyl-5-methoxybenzo[d]isoxazol-3-amine (CAS 1344704-23-9)
- 2-(2-Fluorophenyl)-1h-1,3-benzodiazole (CAS 321-51-7)
- 3-(Bis(2-chloroethyl)amino)benzonitrile (CAS 24813-12-5)
- 2,3-Dibromo-4-(difluoromethyl)-6-iodopyridine (CAS 1805958-67-1)
- ((Cyclopropylmethyl)sulfonyl)benzene (CAS 69563-28-6)
- 2,6-Difluoro-3,5-dimethoxybenzoic acid (CAS 651734-56-4)
- 3-(2-Aminoethyl)-2,3-dihydro-1,3-benzoxazol-2-one (CAS 1016512-75-6)
- 3-{[(2-Methylbenzyl)oxy]methyl}pyrrolidinehydrochloride (CAS 1219949-10-6)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
Why CATO?
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