4-Hydroxy-5-methoxy-2H-chromen-2-one CAS 53666-76-5
| CAS No. | 53666-76-5 |
| Molecular Formula | C10H8O4 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.17 g/mol gives 4-Hydroxy-5-methoxy-2H-chromen-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Hydroxy-5-methoxy-2H-chromen-2-one (CAS 53666-76-5), a certified reference material (molecular formula C10H8O4, MW 192.17 g/mol) for analytical method development and quality control.
4-Hydroxy-5-methoxy-2H-chromen-2-one (C10H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8O4 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Hydroxy Standards
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Recommended Standards
- 4-Hydroxy-3-methylbenzofuran-2-carboxylic acid (CAS 3781-70-2)
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