2-Amino-6-((3,4-dichlorophenyl)sulfonyl)quinazolin-4(1H)-one CAS 53667-27-9

Purity 97%+In StockPharmaceutical Standards
CAS No.53667-27-9
Molecular FormulaC14H9Cl2N3O3S
Molecular Weight370.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-6-((3,4-dichlorophenyl)sulfonyl)quinazolin-4(1H)-one CAS 53667-27-9 chemical structure

Description

The occurrence of 2-Amino-6-((3,4-dichlorophenyl)sulfonyl)quinazolin-4(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Amino-6-((3,4-dichlorophenyl)sulfonyl)quinazolin-4(1H)-one (CAS 53667-27-9), molecular formula C14H9Cl2N3O3S and molecular weight 370.21 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Amino-6-((3,4-dichlorophenyl)sulfonyl)quinazolin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 370.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H9Cl2N3O3S
Molecular Weight370.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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