N-(4-(3-Methoxyphenyl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide CAS 536731-79-0
| CAS No. | 536731-79-0 |
| Molecular Formula | C19H16N2O4S |
| Molecular Weight | 368.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-(3-Methoxyphenyl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide (C19H16N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
N-(4-(3-Methoxyphenyl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide (CAS 536731-79-0), molecular formula C19H16N2O4S and molecular weight 368.41 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16N2O4S |
| Molecular Weight | 368.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide (CAS 477550-42-8)
- N-(2-Methoxyphenyl)-4-(3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazine-1-carboxamide (CAS 1070862-25-7)
- N-(4-(5-((4-Methoxyphenyl)(methyl)amino)-1,3,4-thiadiazol-2-yl)phenyl)propionamide (CAS 1021059-72-2)
- Tris(2-methoxyphenyl)phosphineoxide (CAS 47467-89-0)
- Ethyl 5-(4-methoxyphenyl)-2,4-dioxoimidazolidine-1-carboxylate (CAS 18755-75-4)
- Bis(4-methoxyphenyl) furan-2,4-dicarboxylate (CAS 57467-49-9)
- 1-(3-Methoxyphenyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 1809876-45-6)
- 1-(4-Methoxyphenyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874301-63-0)
Recommended Standards
- Methyl 3-{2-[(cyclopropylcarbamoyl)carbonyl]-1H-pyrrol-1-yl}-1-benzothiophene-2-carboxylate (CAS 477872-71-2)
- Methyl 3-(2-{[(prop-2-en-1-yl)carbamoyl]carbonyl}-1H-pyrrol-1-yl)-1-benzothiophene-2-carboxylate (CAS 477863-31-3)
- N-(4H-Chromeno[4,3-d]thiazol-2-yl)-2,4-dimethoxybenzamide (CAS 681157-61-9)
- Ethyl 2-((6-amino-3,5-dicyano-4-(4-methoxyphenyl)pyridin-2-yl)thio)acetate (CAS 361477-99-8)
- 1-(2-(Benzyloxy)phenyl)propan-2-one (CAS 130936-16-2)
- Methyl 2-bromo-5-formylbenzoate (CAS 1043418-95-6)
- 2,4,5-Trichlorobenzenesulfonamide (CAS 29092-27-1)
- 1-(14-Hydroxy-3,6,9,12-tetraoxatetradecyl)urea (CAS 61775-03-9)
- 6-(1H-Imidazol-1-yl)pyrimidine-4-carboxylic acid (CAS 1097256-19-3)
- tert-Butyl 2-chloro-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate (CAS 1211581-54-2)
- 3-(5,6-Dichloro-1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 338412-08-1)
- 4-(1,3,2-Dioxaborinan-2-yl)benzaldehyde (CAS 160068-88-2)
- Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate (CAS 104036-19-3)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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