Guanicaine CAS 537-05-3
| CAS No. | 537-05-3 |
| Molecular Formula | C23H25N3O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Guanicaine (CAS 537-05-3), molecular formula C23H25N3O3HCl and molecular weight 427.93 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C23H25N3O3HCl, Guanicaine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 427.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H25N3O3 HCl |
| Molecular Weight | 427.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 2-((4-(Furan-2-ylmethyl)-5-(pyridin-3-yl)-4h-1,2,4-triazol-3-yl)thio)acetic acid (CAS 460713-91-1)
- 7-Fluoro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline (CAS 1187933-43-2)
- N-(furan-2-ylmethyl)-2-(4-methoxyphenyl)-1-phenylethan-1-amine (CAS 436087-18-2)
- 4-Isobutoxypicolinimidamide hydrochloride (CAS 1179361-97-7)
- Vortioxetine Impurity 7 (CAS CATO-C4X-10567)
- 2-bromo-N-(2,4-difluorophenyl)butanamide (CAS 924969-60-8)
- 2-Methyl-4-(phenylsulfonyl)morpholine (CAS 1219152-02-9)
- 7-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine (CAS 2168024-03-9)
- 4-Butoxynaphthalene-1,2-dione (CAS 107909-31-9)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com