tert-Butyl 2-chloro-6-methoxyisonicotinate CAS 537032-06-7
| CAS No. | 537032-06-7 |
| Molecular Formula | C11H14ClNO3 |
| Molecular Weight | 243.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), tert-Butyl 2-chloro-6-methoxyisonicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies tert-Butyl 2-chloro-6-methoxyisonicotinate (CAS 537032-06-7), a certified reference material (molecular formula C11H14ClNO3, MW 243.69 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl 2-chloro-6-methoxyisonicotinate (C11H14ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO3 |
| Molecular Weight | 243.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (4-chloro-3-hydroxyphenyl)carbamate (CAS 345893-27-8)
- tert-Butyl 2-chloro-6-methoxynicotinate (CAS 2089378-14-1)
- tert-Butyl (4-chloro-2-hydroxyphenyl)carbamate (CAS 937064-33-0)
- Tert-butyl 3-chloro-2-methoxyisonicotinate (CAS 2413441-21-9)
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