3-(tert-Butyl)-1-(4-fluorobenzyl)-1H-pyrazole-5-carbonyl chloride CAS 537050-09-2
| CAS No. | 537050-09-2 |
| Molecular Formula | C15H16ClFN2O |
| Molecular Weight | 294.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(tert-Butyl)-1-(4-fluorobenzyl)-1H-pyrazole-5-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(tert-Butyl)-1-(4-fluorobenzyl)-1H-pyrazole-5-carbonyl chloride (CAS 537050-09-2), molecular formula C15H16ClFN2O and molecular weight 294.75 g/mol, is a CATO reference standard with documented purity and traceability.
3-(tert-Butyl)-1-(4-fluorobenzyl)-1H-pyrazole-5-carbonyl chloride (C15H16ClFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H16ClFN2O |
| Molecular Weight | 294.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 2-Tosylbenzoyl Chloride (CAS 2006278-16-4)
- 4-((4-Chlorobenzylidene)amino)benzenesulfonamide (CAS 105947-03-3)
- 2-Chloro-6-hydroxy-4-((2-methoxyphenyl)thio)benzaldehyde (CAS 301179-85-1)
- 7-Chloro-N-(2-furylmethyl)-4-methoxy-1,3-benzothiazol-2-amine (CAS 1105189-55-6)
- 4-Methylpiperidin-3-amine (CAS 221221-30-3)
- N-[6-chloro-4-(trifluoromethyl)-2-pyridyl]-N'-(4-methylphenyl)urea (CAS 256471-19-9)
- 3-(3-Amino-4-nitrophenyl)-1-propanol (CAS 849235-84-3)
- Tris(2,5-dimethylphenyl) phosphate (CAS 19074-59-0)
- Trelagliptin impurity 84 (CAS CATO-C4X-104684)
- Pivmecillinam Impurity 13 (CAS CATO-C4X-232313)
- 2,2,6,6-tetradeuteriomorpholine (CAS 35530-94-0)
- Methyl 3-amino-6-(5-methylfuran-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylate (CAS 625377-65-3)
- N-(5-fluoro-2-methylphenyl)tetrahydro-2H-thiopyran-3-amine (CAS 1342044-81-8)
- Peptide Impurity 34 (CAS 21282-09-7)
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