N-(2-morpholinoethyl)-3-(trifluoromethyl)aniline CAS 53725-81-8
| CAS No. | 53725-81-8 |
| Molecular Formula | C13H17F3N2O |
| Molecular Weight | 274.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(2-morpholinoethyl)-3-(trifluoromethyl)aniline (CAS 53725-81-8), a certified reference material (molecular formula C13H17F3N2O, MW 274.28 g/mol) for analytical method development and quality control.
Structurally, N-(2-morpholinoethyl)-3-(trifluoromethyl)aniline (C13H17F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 274.28 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17F3N2O |
| Molecular Weight | 274.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 3-(3-(2-Morpholinoethyl)-1H-1,2,4-triazol-5-yl)aniline (CAS 1279218-85-7)
- 1-(2-Morpholinoethyl)-1h-benzo[d]imidazole-5-carboxylic acid (CAS 1036519-10-4)
- (3-((2-Morpholinoethyl)carbamoyl)phenyl)boronic acid (CAS 957103-92-3)
- (4-((2-Morpholinoethyl)carbamoyl)phenyl)boronic acid (CAS 913835-45-7)
- 3-((2-Morpholinoethyl)sulfonyl)aniline (CAS 1044272-04-9)
- 4-((2-Morpholinoethyl)sulfonyl)aniline (CAS 359010-58-5)
- N-(2-morpholinoethyl)benzenesulfonamide (CAS 349397-02-0)
- N-(2-morpholinoethyl)-2-nitrobenzamide (CAS 120276-16-6)
Recommended Standards
- N-(2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl)benzamide (CAS 55455-18-0)
- N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzamide (CAS 964-04-5)
- N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-hydroxyimino-acetamide (CAS 254991-20-3)
- N,N-diisopropyl-6-(trifluoromethyl)nicotinamide (CAS 765298-12-2)
- Methyl 2-(pyrrolidin-3-yl)thiazole-5-carboxylate hydrochloride (CAS 2137717-09-8)
- 4-(2-Azabicyclo[2.2.1]Heptan-2-yl)benzaldehyde (CAS 1249535-41-8)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
- N-(3-Cyano-5-phenylfuran-2-yl)-4-fluoro-N-(4-fluorobenzenesulfonyl)benzene-1-sulfonamide (CAS 478045-58-8)
- Flucloxacillin impurity 16 (CAS CATO-C4X-164716)
- (2S,3S)-2-Amino-3-methoxybutanoic acid (CAS 104195-80-4)
- N-Benzyl-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775553-83-7)
- 2-(2,6-Difluorophenyl)propan-1-ol (CAS 1521023-94-8)
- 5-Bromo-3-chloro-2-methyl-2H-indazole (CAS 1243288-50-7)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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