Methyl 3-bromo-2-fluoro-5-(trifluoromethyl)benzoate CAS 537658-03-0
| CAS No. | 537658-03-0 |
| Molecular Formula | C9H5BrF4O2 |
| Molecular Weight | 301.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 3-bromo-2-fluoro-5-(trifluoromethyl)benzoate (CAS 537658-03-0), a certified reference material (molecular formula C9H5BrF4O2, MW 301.03 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Methyl 3-bromo-2-fluoro-5-(trifluoromethyl)benzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 301.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-bromo-2-fluoro-5-(trifluoromethyl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrF4O2 |
| Molecular Weight | 301.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
Related Methyl Standards
- Methyl 6-bromo-2-fluoro-3-(trifluoromethyl)benzoate (CAS 1352718-55-8)
- 2-Bromo-1-(2-fluoro-3-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1429321-83-4)
- 2-Bromo-1-(3-fluoro-4-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1448246-57-8)
- 2-(2-Bromo-5-fluoro-4-(trifluoromethyl)phenyl)acetic acid (CAS 2385550-69-4)
- 2-(3-Bromo-2-fluoro-5-(trifluoromethyl)phenyl)acetic acid (CAS 2385623-99-2)
- 2-(3-Bromo-6-fluoro-2-(trifluoromethyl)phenyl)acetic acid (CAS 2385598-79-6)
- 2-(4-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)acetic acid (CAS 2386484-34-8)
- 2-(5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)acetic acid (CAS 2384476-13-3)
Recommended Standards
- Methyl 2-bromo-6-fluoro-3-(trifluoromethyl)benzoate (CAS 2090828-24-1)
- Methyl 3-bromo-2-fluoro-6-(trifluoromethyl)benzoate (CAS 2090828-39-8)
- Methyl 2-bromo-5-fluoro-4-(trifluoromethyl)benzoate (CAS 2092867-63-3)
- Methyl 4-bromo-2-fluoro-3-(trifluoromethyl)benzoate (CAS 2243512-86-7)
- (2S,4R)-2-((R)-2-(2-Hydroxyphenyl)-4,5-dihydrothiazol-4-yl)-3-methylthiazolidine-4-carboxylic acid (CAS 164104-32-9)
- 2-Chloro-5-cyclopropoxy-3-isopropoxypyridine (CAS 1243323-28-5)
- 2-BROMO-5-HYDROXY-3-PICOLINE (CAS 1003711-43-0)
- Nebivolol Impurity 57 (CAS 1346562-35-3 (free base))
- (3-Iodophenyl)(isoquinolin-4-yl)methanone (CAS 1187165-67-8)
- Cyclovirobuxine Impurity 1 (CAS 6908-25-4)
- 2-(2-Amino-3-(difluoromethyl)-5-hydroxypyridin-4-yl)acetic acid (CAS 1805136-17-7)
- Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt (CAS 1802078-33-6)
- 4-Phenyl-1H-pyrazol-3-amine (CAS 5591-70-8)
- Neuropeptide AF (human) (CAS 192387-38-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com