4-(4-Chlorophenyl)-2-methylthiazole-5-carboxylic acid CAS 537712-89-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chlorophenyl)-2-methylthiazole-5-carboxylic acid.

4-(4-Chlorophenyl)-2-methylthiazole-5-carboxylic acid (CAS 537712-89-3), molecular formula C11H8ClNO2S and molecular weight 253.70 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(4-Chlorophenyl)-2-methylthiazole-5-carboxylic acid (C11H8ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(4-Chlorophenyl)-2-methylthiazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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