5-Fluoro-2-(4-trifluoromethylphenyl)benzoic acid CAS 537713-35-2
| CAS No. | 537713-35-2 |
| Molecular Formula | C14H8F4O2 |
| Molecular Weight | 284.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-Fluoro-2-(4-trifluoromethylphenyl)benzoic acid (C14H8F4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 284.21 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Fluoro-2-(4-trifluoromethylphenyl)benzoic acid (CAS 537713-35-2), molecular formula C14H8F4O2 and molecular weight 284.21 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Fluoro-2-(4-trifluoromethylphenyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F4O2 |
| Molecular Weight | 284.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-5-(4-trifluoromethylphenyl)benzoic acid (CAS 1179671-81-8)
- 5-Fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 1179762-71-0)
- 4-Fluoro-3-(3-trifluoromethylphenyl)benzoic acid (CAS 1261593-39-8)
- 2-Fluoro-4'-(trifluoromethyl)biphenyl-3-carboxylic acid (CAS 1261669-11-7)
- 5-Fluoro-3-(2-trifluoromethylphenyl)benzoic acid (CAS 1261741-41-6)
- 3-Fluoro-4-(3-trifluoromethylphenyl)benzoic acid (CAS 1261750-12-2)
- 2-Fluoro-5-(2-trifluoromethylphenyl)benzoic acid (CAS 1261772-06-8)
- 5-Fluoro-3-(3-trifluoromethylphenyl)benzoic acid (CAS 1261772-10-4)
Recommended Standards
- 4-Fluorophenyl 3-(trifluoromethyl)benzoate (CAS 218929-27-2)
- 5-Fluoro-2-[3-(trifluoromethyl)phenyl]benzoic acid (CAS 926200-33-1)
- 4'-Fluoro-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 942475-07-2)
- 6-Fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 378231-10-8)
- 2-Amino-3,3,3-trifluoro-2-(2-methoxyphenyl)propanoic acid (CAS 1406834-27-2)
- 2-(4-(Benzo[c][1,2,5]thiadiazol-5-ylmethyl)piperazin-1-yl)ethan-1-ol (CAS 874834-85-2)
- 1-Iodo-3-(phenethoxymethyl)benzene (CAS 1222138-98-8)
- 898774-88-4 1-(4-Chloro-3-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one DTXSID90644235 (CAS 898774-88-4)
- 4,4-Dimethylazepane-1-sulfonyl chloride (CAS 1494928-34-5)
- 2-Methoxy-5-methylisonicotinaldehyde (CAS 1227515-61-8)
- 5-fluoropyrimidine-2-sulfonyl chloride (CAS 1211537-47-1)
- 6-(2-Chlorophenoxy)-5-fluoro-4(3H)-pyrimidinone (CAS 519002-09-6)
- Methyl 4-((2-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)butanoate (CAS 478046-04-7)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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