Domperidone Impurity 7 CAS 53786-44-0
| CAS No. | 53786-44-0 |
| Molecular Formula | C14H18ClN3O4 |
| Molecular Weight | 327.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 327.76 g/mol gives Domperidone Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Domperidone Impurity 7 (CAS 53786-44-0, C14H18ClN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Domperidone Impurity 7 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Domperidone Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18ClN3O4 |
| Molecular Weight | 327.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Domperidone Standards
- Domperidone Impurity 26 (CAS CATO-C4X-142026)
- Domperidone Impurity 27 (CAS CATO-C4X-142027)
- Domperidone Impurity 37 (CAS CATO-C4X-142037)
- Domperidone Impurity 20 (CAS 53786-46-2)
- Domperidone Impurity 16 (CAS 39677-10-6)
- Domperidone impurity 36 (CAS CATO-C4X-142036)
- Domperidone Impurity 38 (CAS CATO-C4X-142038)
- Domperidone Impurity 12 (CAS 107618-26-8)
Recommended Standards
- Alprazolam EP Impurity B (CAS 38150-27-5)
- Indacaterol Impurity 27 (CAS 63404-86-4)
- N-(3-chlorophenyl)-2-(5-(p-tolyl)-1,2,4-oxadiazol-3-yl)acetamide (CAS 915931-56-5)
- Bepotastine Impurity 25 (CAS CATO-C4X-183925)
- Betaxolol Impurity 19 (CAS CATO-C4X-155919)
- Adefovir Impurity 16 (CAS CATO-C4X-115216)
- Terbinafine EP Impurity D (CAS 151222-50-3)
- (2S,4R)-1-BOC-4-TRIFLUOROMETHYLPYRROLIDINE-2-CARBOXYLIC ACID (CAS 470482-44-1)
- 1,2,2-Trifluoroethyl trifluoromethyl ether (CAS 84011-06-3)
- 1,4-Dihydro-5,8-dimethyl-1,4-epoxynaphthalene (CAS 123674-31-7)
- 5-Chloro-2-iodo-N-isopropylbenzamide (CAS 1147836-22-3)
- 2,2-Dimethyl-1-(2-methylquinolin-3-yl)propan-1-one (CAS 1380602-57-2)
- 1-([1,1'-biphenyl]-4-yl)prop-2-en-1-ol (CAS 170938-13-3)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com