5,8-Dichloroquinolin-4-ol CAS 53790-82-2
| CAS No. | 53790-82-2 |
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5,8-Dichloroquinolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5,8-Dichloroquinolin-4-ol (CAS 53790-82-2) is a high-purity analytical reference standard with the molecular formula C9H5Cl2NO and a molecular weight of 214.05 g/mol.
5,8-Dichloroquinolin-4-ol (C9H5Cl2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloroquinolin Standards
- 6,7-Dichloroquinolin-2(1H)-one (CAS 136472-34-9)
- 7,8-dichloroquinolin-3-ol (CAS 1492660-10-2)
- 3,7-Dichloroquinolin-4-ol (CAS 152210-26-9)
- 4,7-Dichloroquinolin-2(1H)-one (CAS 156820-88-1)
- 5,7-Dichloroquinolin-4-ol (CAS 171850-29-6)
- 2,3-Dichloroquinolin-8-ol (CAS 37396-44-4)
- 2,5-Dichloroquinolin-8-ol (CAS 56550-18-6)
- 3,5-Dichloroquinolin-4-ol (CAS 860502-05-2)
Recommended Standards
- 5,7-Dichloroquinolin-2(1H)-one (CAS 835903-13-4)
- 5-Chloro-1H-indole-2-carbonyl chloride (CAS 64507-05-7)
- 5,7-Dichloro-4-hydroxyquinoline, 97% (CAS 21873-52-9)
- 5-Chloro-3-(4-chlorophenyl)isoxazole (CAS 51726-07-9)
- 1-((1,5-Dimethyl-1H-pyrazol-4-yl)sulfonyl)piperidine-3-carboxylic acid (CAS 957313-95-0)
- Methyl 9-bromo-8-fluoro-4,5-dihydrobenzo[2,3]oxepino[4,5-d]thiazole-2-carboxylate (CAS 1555704-86-3)
- 2-Tosylcyclohexan-1-amine (CAS 1146290-47-2)
- Methyl 3-(2-bromo-5-fluorophenyl)propanoate (CAS 1261855-30-4)
- 7-(Benzyloxy)chroman-4-one (CAS 31042-20-3)
- 1-(Oxetan-3-yl)-1H-imidazol-4-amine (CAS 1434053-40-3)
- 1,4-Diamino-2-((6-hydroxyhexyl)oxy)anthracene-9,10-dione (CAS 95618-39-6)
- Mosapride Impurity 62 (CAS CATO-C4X-104462)
- 6-Ethyl-3-methylquinoline-2-thiol (CAS 917749-59-8)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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