Diphenyl phosphorochloridite CAS 5382-00-3
| CAS No. | 5382-00-3 |
| Molecular Formula | C12H10ClO2P |
| Molecular Weight | 252.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diphenyl phosphorochloridite (CAS 5382-00-3) is a high-purity analytical reference standard with the molecular formula C12H10ClO2P and a molecular weight of 252.63 g/mol.
Owing to organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Diphenyl phosphorochloridite is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Diphenyl phosphorochloridite meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClO2P |
| Molecular Weight | 252.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
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- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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