5-Benzylidene-3-(4-chlorophenyl)-2-thioxoimidazolidin-4-one CAS 53865-27-3
| CAS No. | 53865-27-3 |
| Molecular Formula | C16H11ClN2OS |
| Molecular Weight | 314.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Benzylidene-3-(4-chlorophenyl)-2-thioxoimidazolidin-4-one (CAS 53865-27-3) is a high-purity analytical reference standard with the molecular formula C16H11ClN2OS and a molecular weight of 314.79 g/mol.
The molecular framework of 5-Benzylidene-3-(4-chlorophenyl)-2-thioxoimidazolidin-4-one (C16H11ClN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN2OS |
| Molecular Weight | 314.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- N-(4-Methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1259285-57-8)
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- 2,4-Diamino-6-methoxy-1,3,5-triazine Solution, 1,000 mg/L, 1ml (CAS 2827-45-4)
- Prednisolone impurity 66 (CAS 137759-50-3)
- MEthyl 1-(3-methoxyphenyl)-2,3,4,9-tetrahydro-1h-beta-carboline-3-carboxylate, HCl (CAS 1214827-69-6)
- 3-(4-Chloro-2,5-dimethylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (CAS 400078-20-8)
- 3-Chloro-6-cyclopropylanisole (CAS 1095539-56-2)
- 5-((3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-ethyl-2-thioxothiazolidin-4-one (CAS 371773-71-6)
- 4-Methoxyphenyl 5-chloro-2-(methylthio)pyrimidine-4-carboxylate (CAS 879958-04-0)
- Peptide 433 (CAS CATO-CPTD788433)
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