(S)-N-((R)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide CAS 53933-27-0
| CAS No. | 53933-27-0 |
| Molecular Formula | C14H25N3O3 |
| Molecular Weight | 283.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S)-N-((R)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide.
(S)-N-((R)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide (CAS 53933-27-0), molecular formula C14H25N3O3 and molecular weight 283.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-N-((R)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide (C14H25N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-N-((R)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H25N3O3 |
| Molecular Weight | 283.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 3 |
Recommended Standards
- (E)-8-Methyl-2-(2-(naphthalen-1-yl)vinyl)indolizine (CAS 314731-96-9)
- (S)-N-((S)-1-Amino-1-oxopropan-2-yl)-N-methyl-1-pivaloylpyrrolidine-2-carboxamide (CAS 53933-24-7)
- (2-(4-Methyl-2-phenylpiperazin-1-yl)pyridin-3-yl)methanol (CAS 337376-18-8)
- 1-(2-(Cyclohex-1-en-1-yl)ethyl)-3-(1H-indol-3-yl)urea (CAS 900006-49-7)
- 3-Bromo-4,5,7-trichloroquinoline (CAS 1204811-37-9)
- 4-cyclopropyl-5-(piperidin-4-yl)-4H-1,2,4-triazole-3-thiol hydrochloride (CAS 1158449-20-7)
- N-Cyclohexyl-3-(1-tosylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352531-90-8)
- 3,10-Dibromoperylene (CAS 85514-20-1)
- 2'-Chloro-2,3,4,5-tetrahydro-1,1'-biphenyl (CAS 17465-36-0)
- 4-Amino-3-(2-(dimethylamino)ethyl)-6,7-dimethoxyquinazoline-2(3H)-thione (CAS 400751-59-9)
- N-(4-isopropylthiazol-2-yl)piperidine-4-carboxamide hydrochloride (CAS 1606887-60-8)
- 2-Fluoro-3-trifluoromethylsulfanylpyrazine (CAS 1206524-61-9)
- 3-(Pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1151768-87-4)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com