Hydroxy cyclophosphamide Semicarbazone CAS 53948-46-2

Purity 97%+In StockPharmaceutical Standards
CAS No.53948-46-2
Molecular FormulaC8H18Cl2N5O3P
Molecular Weight334.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Hydroxy cyclophosphamide Semicarbazone CAS 53948-46-2 chemical structure

Description

The occurrence of Hydroxy cyclophosphamide Semicarbazone is closely related to an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Hydroxy cyclophosphamide Semicarbazone (CAS 53948-46-2) is a high-purity analytical reference standard with the molecular formula C8H18Cl2N5O3P and a molecular weight of 334.14 g/mol.

The molecular framework of Hydroxy cyclophosphamide Semicarbazone (C8H18Cl2N5O3P) is characterized by an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Hydroxy cyclophosphamide Semicarbazone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H18Cl2N5O3P
Molecular Weight334.14 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.5
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms5

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