Dimethyl 2-(2-nitrophenethyl)malonate CAS 5395-45-9

Purity 97%+In StockPharmaceutical Standards
CAS No.5395-45-9
Molecular FormulaC13H15NO6
Molecular Weight281.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Dimethyl 2-(2-nitrophenethyl)malonate CAS 5395-45-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 281.26 g/mol gives Dimethyl 2-(2-nitrophenethyl)malonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Dimethyl 2-(2-nitrophenethyl)malonate (CAS 5395-45-9), a certified reference material (molecular formula C13H15NO6, MW 281.26 g/mol) for analytical method development and quality control.

The molecular framework of Dimethyl 2-(2-nitrophenethyl)malonate (C13H15NO6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Dimethyl 2-(2-nitrophenethyl)malonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H15NO6
Molecular Weight281.26 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms1

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