3,3-Difluoro-3-(4-fluorophenyl)-2-hydroxypropionic acid CAS 541508-26-3
| CAS No. | 541508-26-3 |
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3-Difluoro-3-(4-fluorophenyl)-2-hydroxypropionic acid (CAS 541508-26-3) is a high-purity analytical reference standard with the molecular formula C9H7F3O3 and a molecular weight of 220.15 g/mol.
Based on its molecular formula C9H7F3O3, 3,3-Difluoro-3-(4-fluorophenyl)-2-hydroxypropionic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 220.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-Difluoro-3-(4-fluorophenyl)-2-hydroxypropionic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,2-Difluoro-2-(3-fluoro-4-methoxyphenyl)acetic acid (CAS 1027513-93-4)
- 2,2-Difluoro-2-(5-fluoro-2-methoxyphenyl)acetic acid (CAS 1375473-08-7)
- Methyl 2,2-difluoro-2-(4-fluorophenoxy)acetate (CAS 338792-43-1)
- Ethyl 2,2-difluoro-3-(furan-2-yl)-3-hydroxypropanoate (CAS 118460-43-8)
- 3,3-difluoro-5-nitro-2,3-dihydro-1H-indol-2-one (CAS 197067-34-8)
- 2,2-Difluoro-2-(3-(methoxycarbonyl)bicyclo[1.1.1]Pentan-1-yl)acetic acid (CAS 2166577-94-0)
- 2,4'-Difluoro-4-methoxybiphenyl (CAS 1214346-71-0)
- (4',5-Difluoro-[1,1'-biphenyl]-3-yl)methanol (CAS 1214359-09-7)
Recommended Standards
- 3,3,3-Trifluoro-2-hydroxy-2-phenylpropanoic acid (CAS 55519-22-7)
- 3-Allyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 26676-05-1)
- 3-(Trifluoromethoxy)phenylacetic Acid (CAS 203302-97-0)
- 3-Methoxy-4-(trifluoromethyl)benzoic Acid (CAS 276861-63-3)
- Rel-(3R,5R)-5-methylpiperidine-3-carboxylic acid (CAS 110287-72-4)
- 3-Chloro-4,5-bis(2-methylphenyl)-4h-1,2,4-triazole (CAS 1087784-52-8)
- 1-4-β-D-Mannotriose (CAS 28173-52-6)
- N-(2-Hydroxy-2-methyl-4-(methylthio)butyl)-3-(phenylthio)propanamide (CAS 1396746-21-6)
- 1-(2-Ethoxypropoxy)propan-2-ol (CAS 10143-32-5)
- 4-Amino-N-(1H-pyrazolo[3,4-b]pyridin-4-yl)benzamide (CAS 370589-25-6)
- 2-Iodo-N,N-dimethylethan-1-amine hydroiodide (CAS 76004-08-5)
- (1R,2S)-2-(2-methoxybenzoyl)cyclohexane-1-carboxylic acid (CAS 733742-61-5)
- Ethyl 2-(4-(hydroxymethyl)phenoxy)acetate (CAS 103258-64-6)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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