5-(3,4-Dimethoxy-phenyl)-[1,3,4]thiadiazol-2-ylamine CAS 5427-87-2
| CAS No. | 5427-87-2 |
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3,4-Dimethoxy-phenyl)-[1,3,4]thiadiazol-2-ylamine (CAS 5427-87-2), molecular formula C10H11N3O2S and molecular weight 237.28 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(3,4-Dimethoxy-phenyl)-[1,3,4]thiadiazol-2-ylamine (C10H11N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 237.28 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(3,4-Dimethoxy-phenyl)-[1,3,4]thiadiazol-2-ylamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethoxy Standards
- N-(4,5-dimethoxy-2-methylphenyl)isobutyramide (CAS 1090610-88-0)
- (5,6-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-8-yl)methanol (CAS 87664-90-2)
- 1-(3,4-Dimethoxy-pyridin-2-ylmethyl)-piperazine (CAS 1517234-23-9)
- 2,5-Dimethoxy-4,β-dimethyl-β-nitrostyrene (CAS 143823-24-9)
- 2,5-dimethoxy-N-acetoacet anilide (CAS 6375-27-5)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 41143-95-7)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 76824-86-7)
- 2,5-Dimethoxy-4-propylamphetamine (CAS 63779-88-4)
Recommended Standards
- 5-(2,5-Dimethoxyphenyl)-1,3,4-thiadiazol-2-amine (CAS 88742-90-9)
- 5-(3,5-Dimethoxyphenyl)-1,3,4-thiadiazol-2-amine (CAS 383130-39-0)
- 5-(2,4-Dimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 928710-74-1)
- 5-(Ethylsulfonyl)-3-phenyl-1H-1,2,4-triazole (CAS 924663-88-7)
- 2-Amino-N-isopropyl-N-(4-(methylthio)benzyl)acetamide (CAS 1353983-29-5)
- (3-Phenyl-4,5-dihydroisoxazol-5-yl)methanol (CAS 1569-94-4)
- 5-Chloro-2-thienylmagnesium bromide, 0.25M 2-MeTHF (CAS 111762-30-2)
- 2-((3-Phenyl-1,2,4-oxadiazol-5-yl)amino)ethanol (CAS 7627-09-0)
- 6-Methyl-1,3-diazaspiro[4.5]decane-2,4-dione (CAS 707-15-3)
- N-Nitrosodiphenylamine (CAS 86-30-6)
- 2-((3-Methylpyridin-4-yl)methyl)azepane (CAS 881040-70-6)
- Ethyl 1-(5-bromopyridin-3-yl)piperidine-4-carboxylate (CAS 847406-13-7)
- 4-(4-Chlorophenyl)dibenzofuran (CAS 1369509-91-0)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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