Warfarin Impurity 15 CAS 54288-86-7
| CAS No. | 54288-86-7 |
| Molecular Formula | C19H16O4 |
| Molecular Weight | 308.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Warfarin Impurity 15 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Warfarin Impurity 15 (CAS 54288-86-7, C19H16O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, Warfarin Impurity 15 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16O4 |
| Molecular Weight | 308.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Warfarin Standards
- S-(-)-Warfarin (CAS 5543-57-7)
- R-(+)-Warfarin (CAS 5543-58-8)
- Warfarin impurity 15 (CAS CATO-C4X-17815)
- Warfarin (CAS 81-81-2)
- Warfarin Alcohol (Mixture of Diastereomers) (CAS 28392-96-3)
- Warfarin Impurity 13 (CAS CATO-C4X-142913)
- Warfarin impurity 14 (CAS CATO-C4X-17814)
- Warfarin Impurity 7 (CAS 67588-18-5)
Recommended Standards
- Domperidone Impurity 16 (CAS 39677-10-6)
- N-Nitroso Ondansetron impurity 30 (CAS CATO-C4X-139430)
- Carbamazepine Impurity 15 (CAS CATO-C4X-118115)
- Loxoprofen impurity 124 (CAS CATO-C4X-1488124)
- Acalabrutinib Impurity 30 (CAS CATO-C4X-305530)
- Carbazochrome Impurity 27 (CAS CATO-C4X-229127)
- Mosapride Impurity 48 (CAS CATO-C4X-104448)
- 2-Methyl-1-[3-(trifluoromethyl)phenyl]propan-1-amine (CAS 1021032-89-2)
- (S)-2-methoxy-1-(p-tolyl)ethan-1-amine (CAS 1270100-20-3)
- 2-((5-(4-(tert-Butyl)phenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-1-(3-methoxyphenyl)ethanone (CAS 579440-57-6)
- 5-Bromo-2-chloro-N-(pyrrolidin-3-yl)benzamide (CAS 1830456-72-8)
- 4-Amino-2-bromophenol (CAS 16750-67-7)
- 1-BRomo-4-ethoxy-2,5-dimethylbenzene (CAS 482355-53-3)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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