1-Acetyl-4-chloro-2-methyl-1H-indol-3-yl acetate CAS 5446-21-9
| CAS No. | 5446-21-9 |
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Acetyl-4-chloro-2-methyl-1H-indol-3-yl acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Acetyl-4-chloro-2-methyl-1H-indol-3-yl acetate (CAS 5446-21-9), molecular formula C13H12ClNO3 and molecular weight 265.69 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H12ClNO3, 1-Acetyl-4-chloro-2-methyl-1H-indol-3-yl acetate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1-(2-Chloro-6,7-dimethoxyquinolin-3-yl)ethanone (CAS 94741-42-1)
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- 2-((2-Chloro-3-oxocyclohex-1-en-1-yl)amino)benzoic acid (CAS 937604-82-5)
- 7-(Allyloxy)-4-methyl-2H-chromen-2-one (CAS 3993-57-5)
- ethyl 2-bromo-4-chloro-6-fluorobenzoate (CAS 1805575-80-7)
- 1-(3,4-Diethoxybenzyl)-1h-pyrazol-4-amine (CAS 1002033-47-7)
- 2-Bromo-4-{[(butan-2-yl)amino]methyl}-6-methoxyphenol (CAS 1019551-83-7)
- Methyl 1-methyl-5-thioxopyrrolidine-3-carboxylate (CAS 174747-39-8)
- Ethyl 5-amino-2-methylpyrimidine-4-carboxylate (CAS 1393541-03-1)
- Ni (CAS CATO-CCRM106030)
- 1-(1H-benzimidazol-2-yl)-3-(methylthio)propan-1-amine dihydrochloride (CAS 1171352-71-8)
- 5-Bromo-1-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole (CAS 1956323-01-5)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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