2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one CAS 5452-19-7
| CAS No. | 5452-19-7 |
| Molecular Formula | C9H13N3O2 |
| Molecular Weight | 195.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one (CAS 5452-19-7), molecular formula C9H13N3O2 and molecular weight 195.22 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 195.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H13N3O2 |
| Molecular Weight | 195.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
Related Amino Standards
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Recommended Standards
- 2-Amino-5-(propan-2-yloxy)benzoic acid (CAS 68701-42-8)
- 2-Amino-6-isobutylpyrimidine-4-carboxylic acid (CAS 938458-90-3)
- 2-Amino-5-(piperazin-1-yl)pyrimidin-4(1H)-one (CAS 500596-24-7)
- 2-Amino-6-phenylnicotinonitrile (CAS 56162-65-3)
- 1-(Bromomethyl)-4-(4-(trifluoromethyl)phenoxy)benzene (CAS 117114-01-9)
- 3-Bromo-4-methyl-1,5-naphthyridin-2-amine (CAS 1820683-25-7)
- (-)2'-epi-5-Deoxy-strigol (CAS 1259948-85-0)
- 4-Chloro-1-methyl-5-(trifluoromethyl)-1h-pyrazole-3-carbohydrazide (CAS 1001519-39-6)
- 2-(4-(((Benzyloxy)carbonyl)amino)phenyl)acetic acid (CAS 17859-70-0)
- 1-(3-(4-Bromophenoxy)propyl)pyrrolidine (CAS 92104-90-0)
- Methyl 3-(6-chloropyrazin-2-yl)benzoate (CAS 1194374-28-1)
- ((4-(Acryloyloxy)butanoyl)azanediyl)bis(ethane-2,1-diyl) diacrylate (CAS 66028-34-0)
- Hexachloromethyl-hexamethoxycalix-[6]arene (CAS 124006-38-8)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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