545349-40-4 3-Chloro-N-(5-nitropyridin-2-yl)propanamide MFCD03388031 CAS 545349-40-4
| CAS No. | 545349-40-4 |
| Molecular Formula | C8H8ClN3O3 |
| Molecular Weight | 229.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 545349-40-4 3-Chloro-N-(5-nitropyridin-2-yl)propanamide MFCD03388031.
545349-40-4 3-Chloro-N-(5-nitropyridin-2-yl)propanamide MFCD03388031 (CAS 545349-40-4), molecular formula C8H8ClN3O3 and molecular weight 229.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 545349-40-4 3-Chloro-N-(5-nitropyridin-2-yl)propanamide MFCD03388031 (C8H8ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3O3 |
| Molecular Weight | 229.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 8-Chloro-2,3-dihydroquinolin-4(1H)-one (CAS 21617-11-8)
- 5-(2-Cyclopropylpyrimidin-4-yl)-4-methylthiazol-2-amine (CAS 790707-05-0)
- 8-Benzyloxy Warfarin (CAS 32492-96-9)
- Ethyl 4-bromo-2-[2-(2-methoxyphenyl)-hydrazin-1-ylidene]-3-oxobutanoate (CAS 24129-26-8)
- Benzaldehyde, 4,4',4''-(1,3,5-triazine-2,4,6-triyl)tris-, polymer with 5'-(4-aminophenyl)[1,1':3',1''-terphenyl]-4,4''-diamine (CAS 2230670-46-7)
- 4-Chloro-2,3-dimethylbenzonitrile (CAS 90537-14-7)
- 1-N-(4-methylphenyl)benzene-1,2-diamine (CAS 91806-09-6)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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