4-(4-Methoxyphenyl)-4-methyl-2-phenyloxazol-5(4H)-one CAS 545377-43-3
| CAS No. | 545377-43-3 |
| Molecular Formula | C17H15NO3 |
| Molecular Weight | 281.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Methoxyphenyl)-4-methyl-2-phenyloxazol-5(4H)-one (CAS 545377-43-3) is a high-purity analytical reference standard with the molecular formula C17H15NO3 and a molecular weight of 281.31 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 4-(4-Methoxyphenyl)-4-methyl-2-phenyloxazol-5(4H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(4-Methoxyphenyl)-4-methyl-2-phenyloxazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15NO3 |
| Molecular Weight | 281.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 1 |
Related Methoxyphenyl Standards
- 3,4-Bis(4-methoxyphenyl)isoxazole (CAS 138584-27-7)
- (1-(4-Methoxyphenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol (CAS 618383-39-4)
- 2-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 217493-71-5)
- 3-((4-Methoxyphenyl)amino)-1-phenyl-1H-pyrazol-5(4H)-one (CAS 7186-67-6)
- 3-((4-Methoxyphenyl)diazenyl)-1-methyl-1H-indol-2-ol (CAS 303984-92-1)
- 3-(2-Methoxyphenyl)-5-(4-methoxyphenyl)isoxazole (CAS 89263-89-8)
- 3-(4-Methoxyphenyl)-5-(phenoxymethyl)-1,2-oxazole (CAS 478066-51-2)
- 3,5-Bis(4-methoxyphenyl)isoxazole (CAS 52751-67-4)
Recommended Standards
- 4-(4-Methoxybenzyl)-3-phenylisoxazol-5(2H)-one (CAS 89114-11-4)
- 4-(Ethylsulfurate Sulfonyl)aniline (CAS 2494-89-5)
- 4-(4-(Benzyloxy)phenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-34-1)
- 4-(Tert-butylamino)-6-morpholino-1,3,5-triazine-2-carboxylic acid (CAS 626223-45-8)
- 2-(2-Methoxyethoxy)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2490666-05-0)
- 5-Isopropyl-1-phenyl-1H-pyrazole (CAS 3191-88-6)
- (3-(Oxazol-5-yl)phenyl)methanamine (CAS 857283-83-1)
- 6-(1H-pyrrol-1-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 343372-90-7)
- Atrasentan Impurity 138 (CAS 1058349-16-8)
- (S)-N,N-Dimethyl-1-(piperidin-2-yl)methanamine (CAS 112419-07-5)
- Methyl 4-amino-2-(phenylamino)thiazole-5-carboxylate (CAS 13807-17-5)
- tert-Butyl (4-(hydroxymethyl)oxazol-2-yl)carbamate (CAS 566206-01-7)
- (1,3-Di-p-tolyl-1H-pyrazol-4-yl)methanol (CAS 618444-54-5)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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