2’,5’-Bis(trifluoromethyl)acetophenone CAS 545410-47-7

Purity 97%+In StockPharmaceutical Standards
CAS No.545410-47-7
Molecular FormulaC10H6F6O
Molecular Weight256.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2’,5’-Bis(trifluoromethyl)acetophenone CAS 545410-47-7 chemical structure

Description

The occurrence of 2’,5’-Bis(trifluoromethyl)acetophenone is closely related to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2’,5’-Bis(trifluoromethyl)acetophenone (CAS 545410-47-7), a certified reference material (molecular formula C10H6F6O, MW 256.14 g/mol) for analytical method development and quality control.

Based on its molecular formula C10H6F6O, 2’,5’-Bis(trifluoromethyl)acetophenone contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 256.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H6F6O
Molecular Weight256.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing

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