5-Amino-3-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one CAS 5457-90-9

Purity 97%+In StockPharmaceutical Standards
CAS No.5457-90-9
Molecular FormulaC14H21N4O2S
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-3-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one CAS 5457-90-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-3-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one.

CATO supplies 5-Amino-3-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one (CAS 5457-90-9), a certified reference material (molecular formula C14H21N4O2SCl, MW 344.86 g/mol) for analytical method development and quality control.

5-Amino-3-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one (C14H21N4O2SCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H21N4O2S Cl
Molecular Weight344.86 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentCl-containing
Nitrogen Atoms4
Sulfur Atoms1

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