2H-Isoxazolo[4,5-b]indole CAS 54618-57-4
| CAS No. | 54618-57-4 |
| Molecular Formula | C9H6N2O |
| Molecular Weight | 158.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2H-Isoxazolo[4,5-b]indole (CAS 54618-57-4), molecular formula C9H6N2O and molecular weight 158.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 2H-Isoxazolo[4,5-b]indole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 158.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2H-Isoxazolo[4,5-b]indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O |
| Molecular Weight | 158.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
Related H Standards
- Isoxazolo[5,4-f]indolizine (CAS 105583-52-6)
- Isoxazolo[5,4-e]indolizine (CAS 110799-54-7)
- 2H-Isoxazolo[4,5-f]isoindole (CAS 118716-69-1)
- Isoxazolo[4,3-g]indolizine (CAS 125612-97-7)
- 2H-Isoxazolo[3,4,5-de]quinoline (CAS 130201-75-1)
- 1H-Isoxazolo[3,4-b]indole (CAS 140469-00-7)
- 2H-Isoxazolo[5,4-f]indole (CAS 146781-77-3)
- 2H-Isoxazolo[4,5-f]indole (CAS 146781-78-4)
Recommended Standards
- 2H-Isoxazolo[3,4,5-de]isoquinoline (CAS 885676-07-3)
- 2H-Isoxazolo[5,4-b]indole (CAS 55156-75-7)
- 2-Ethoxy-4,5-dihydro-1H-imidazole-1-carboxylic acid (CAS 727968-25-4)
- 2H-Isoxazolo[5,4-e]indole (CAS 42394-74-1)
- Ethyl 3-Ethoxy-5-methylbenzoate (CAS 1126430-96-3)
- 1,1'-(Butane-1,4-diyl)bis(1,4-diazabicyclo[2.2.2]Octan-1-ium) bromide (CAS 94630-50-9)
- Spiro[3.3]heptan-1-ol (CAS 1823960-41-3)
- tert-Butyl N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-en-1-yl]carbamate (CAS 1175298-10-8)
- Tert-butyl (3R,4R)-3-((2-(cyclohex-1-en-1-yl)ethyl)amino)-4-hydroxypyrrolidine-1-carboxylate (CAS 1186646-20-7)
- Metoprolol impurity 45 (CAS CATO-C4X-136745)
- tert-Butyl 4-(cyclopropyl(pyridin-4-ylmethyl)carbamoyl)piperidine-1-carboxylate (CAS 1417793-49-7)
- 1-Benzylazetidin-3-ol hydrochloride (CAS 223382-13-6)
- 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine Dihydrochloride (CAS 165377-44-6)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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