1-(4-Fluorophenyl)pyrrolidin-2-one CAS 54660-08-1

Purity 97%+In StockPharmaceutical Standards
CAS No.54660-08-1
Molecular FormulaC10H10FNO
Molecular Weight179.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Fluorophenyl)pyrrolidin-2-one CAS 54660-08-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 179.19 g/mol gives 1-(4-Fluorophenyl)pyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(4-Fluorophenyl)pyrrolidin-2-one (CAS 54660-08-1) is a high-purity analytical reference standard with the molecular formula C10H10FNO and a molecular weight of 179.19 g/mol.

1-(4-Fluorophenyl)pyrrolidin-2-one (C10H10FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Fluorophenyl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10FNO
Molecular Weight179.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentF-containing
Nitrogen Atoms1

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