4-(Chloromethyl)-2-(2-thienyl)thiazole CAS 54679-16-2
| CAS No. | 54679-16-2 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Chloromethyl)-2-(2-thienyl)thiazole (CAS 54679-16-2) is a high-purity analytical reference standard with the molecular formula C22H27NO2 and a molecular weight of 337.46 g/mol.
The molecular framework of 4-(Chloromethyl)-2-(2-thienyl)thiazole (C22H27NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2,2'-Bis(chloromethyl)-1,1'-binaphthalene (CAS 96693-27-5)
- 2-(Chloromethyl)dibenzo[b,d]furan (CAS 77358-96-4)
- 2-(Chloromethyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 312510-67-1)
- 2-(Chloromethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 53691-80-8)
- Ethyl 6-(chloromethyl)-4-(4-ethoxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1232790-12-3)
- (((4-(Chloromethyl)-1,2-phenylene)bis(oxy))bis(methylene))dibenzene (CAS 1699-59-8)
- (((5-(Chloromethyl)-1,3-phenylene)bis(oxy))bis(methylene))dibenzene (CAS 67093-27-0)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 4-((5-Ethylthiophen-2-yl)sulfonyl)-2-phenylmorpholine (CAS 946292-18-8)
- 4-[[[2-(Diethylamino)ethyl]amino]carbonyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester (CAS 590424-04-7)
- 3-Methyl-N-{4-[4-(propan-2-yl)piperazin-1-yl]phenyl}benzamide (CAS 478065-80-4)
- 4-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-1,3-thiazol-2-amine (CAS 926240-09-7)
- Cyclopentyl(2,4-difluorophenyl)methanamine (CAS 1021067-83-3)
- 4-Isopropyl-2-oxopyrrolidine-3-carboxylic acid (CAS 90088-26-9)
- 2-(1-methylpiperidin-2-yl)acetic acid (CAS 107388-72-7)
- 2-(2-(Pyrazin-2-yl)thiazol-4-yl)ethan-1-amine (CAS 1060817-06-2)
- Potassium trifluoro((4-fluorophenyl)ethynyl)borate (CAS 1296155-59-3)
- (S)-3-(bromomethyl)tetrahydrofuran (CAS 1616806-50-8)
- 5-Iodo-6-(trifluoromethyl)nicotinic acid (CAS 1805028-51-6)
- 4-(Trifluoroacetamido)benzene-1-sulfonyl chloride (CAS 31143-71-2)
- 3-(Methylamino)-N,3-dimethyl-butanamide (CAS 859195-79-2)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com