4-(3-Hydroxybenzylidene)-3-phenylisoxazol-5(4H)-one CAS 54754-44-8
| CAS No. | 54754-44-8 |
| Molecular Formula | C16H11NO3 |
| Molecular Weight | 265.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3-Hydroxybenzylidene)-3-phenylisoxazol-5(4H)-one.
4-(3-Hydroxybenzylidene)-3-phenylisoxazol-5(4H)-one (CAS 54754-44-8) is a high-purity analytical reference standard with the molecular formula C16H11NO3 and a molecular weight of 265.26 g/mol.
Based on its molecular formula C16H11NO3, 4-(3-Hydroxybenzylidene)-3-phenylisoxazol-5(4H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11NO3 |
| Molecular Weight | 265.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Hydroxybenzylidene Standards
- 4-(2-Hydroxybenzylidene)-3-phenylisoxazol-5(4H)-one (CAS 54754-45-9)
- 4-(3-Hydroxybenzylidene)-2-phenyloxazol-5(4H)-one (CAS 76505-93-6)
- N'-(4-Hydroxybenzylidene)-2-morpholinoacetohydrazide (CAS 61221-00-9)
- N-(2-Hydroxybenzylidene)benzenesulfonamide (CAS 31367-09-6)
- (S)-2-((2-Hydroxybenzylidene)amino)-3-(1H-imidazol-4-yl)propanoic acid (CAS 63546-38-3)
- (E)-2-(2-hydroxybenzylidene)-N-phenylhydrazine-1-carbothioamide (CAS 1185908-30-8)
- N'-(4-Hydroxybenzylidene)-3-isopropyl-1H-pyrazole-5-carbohydrazide (CAS 303106-44-7)
- 2-(2-Hydroxybenzylidene)-2,5,6,7,8,9-hexahydro-3H-imidazo[1,2-a]azepin-3-one (CAS 306955-93-1)
Recommended Standards
- 4-(4-Cyanobenzoyl)phenyl acetate (CAS 890099-56-6)
- 4-(3-Cyanobenzoyl)phenyl acetate (CAS 890099-54-4)
- 4-(5-Hydroxy-1-oxo-1,2-dihydroisoquinolin-4-yl)benzaldehyde (CAS 656234-29-6)
- 4,5,6-Trimethoxy-1-methyl-1h-indole-2-carboxylic acid (CAS 481074-71-9)
- 2-Amino-1-[4-(4-chlorophenyl)piperazin-1-yl]ethan-1-one (CAS 770699-74-6)
- Pseudopelletierine oxime (CAS 6164-67-6)
- 2-Butylsuccinic acid (CAS 1457-39-2)
- 1-Allyl-1h-indol-5-amine (CAS 351324-59-9)
- 4-[(4-Chlorophenyl)sulfanyl]-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-08-9)
- (5-Fluoro-2-propoxyphenyl)boronic Acid (CAS 480438-73-1)
- (2R,3R,4S,5R)-2-{12-chloro-3-methyl-3,7,9,11-tetraazatricyclo[6.4.0.0²,⁶]dodeca-1(12),2(6),4,8,10-pentaen-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol (CAS 2180983-52-0)
- 2-(1-Methyl-3-phenyl-1h-1,2,4-triazol-5-yl)ethan-1-amine dihydrochloride (CAS 1427378-77-5)
- 4-Carboxy-1-(4-carboxybenzyl)pyridin-1-ium bromide (CAS 1451254-94-6)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
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