7-Fluoro-3-(methylthio)-4-nitro-1H-indole CAS 548457-95-0
| CAS No. | 548457-95-0 |
| Molecular Formula | C9H7FN2O2S |
| Molecular Weight | 226.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-Fluoro-3-(methylthio)-4-nitro-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 7-Fluoro-3-(methylthio)-4-nitro-1H-indole (CAS 548457-95-0), a certified reference material (molecular formula C9H7FN2O2S, MW 226.23 g/mol) for analytical method development and quality control.
7-Fluoro-3-(methylthio)-4-nitro-1H-indole (C9H7FN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H7FN2O2S |
| Molecular Weight | 226.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 7,8-Dimethyltetrazolo[1,5-a]quinoline-4-carbaldehyde (CAS 889939-65-5)
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- 6-Phenyl-1,3-benzodioxole-5-carbaldehyde (CAS 4432-95-5)
- 7-Methoxypyrimido[4,5-b]quinolin-2-amine (CAS 582334-06-3)
- tert-butyl 3-(5-bromo-6-chloro-3-pyridyl)-3-methyl-piperazine-1-carboxylate (CAS 2357323-70-5)
- 1,3-dihydro-2-benzofuran-5-sulfonyl chloride (CAS 1151512-23-0)
- 2-(4-((4-Fluorophenyl)carbamoyl)phenoxy)acetic acid (CAS 686282-68-8)
- 3-Bromo-6-ethylpicolinic acid (CAS 2585650-20-8)
- trans-(15S)-Latanoprost (CAS 1235141-39-5)
- 2-(2-Amino-5-chloro-4-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1803672-29-8)
- Spiro[4.5]decan-8-ol (CAS 1266120-78-8)
- Copper iodo[tris(2-methylphenyl)phosphine]- (CAS 143015-26-3)
- 2,3-Dichloro-5-methylbenzaldehyde (CAS 1803824-18-1)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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