Methyl 3-(3-chloropropanamido)thiophene-2-carboxylate CAS 549478-39-9
| CAS No. | 549478-39-9 |
| Molecular Formula | C9H10ClNO3S |
| Molecular Weight | 247.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 3-(3-chloropropanamido)thiophene-2-carboxylate (CAS 549478-39-9), molecular formula C9H10ClNO3S and molecular weight 247.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-(3-chloropropanamido)thiophene-2-carboxylate (C9H10ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Methyl 3-(3-chloropropanamido)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10ClNO3S |
| Molecular Weight | 247.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 3-(2-chloroacetamido)-4-methylthiophene-2-carboxylate (CAS 87685-13-0)
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- Thiamethoxam-urea (CAS 902493-06-5)
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- Ethyl 1-(3-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylate (CAS 618092-34-5)
- 1-(Cyclopropylmethyl)cyclopropanemethanamine Hydrochloride (CAS 1439899-57-6)
- 3-Bromo-<I>N</I>,<I>N</I>-dimethylaniline (CAS 16518-62-0)
- 1-(4-Ethylphenyl)-3-phenylurea (CAS 200134-22-1)
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