2-Fluoro-4-(2-hydroxyethyl)phenol CAS 5497-21-2
| CAS No. | 5497-21-2 |
| Molecular Formula | C8H9FO2 |
| Molecular Weight | 156.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-Fluoro-4-(2-hydroxyethyl)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 156.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Fluoro-4-(2-hydroxyethyl)phenol (CAS 5497-21-2), molecular formula C8H9FO2 and molecular weight 156.15 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Fluoro-4-(2-hydroxyethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9FO2 |
| Molecular Weight | 156.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (2-Fluoro-1,3-phenylene)dimethanol (CAS 1156520-40-9)
- 1-Fluoro-2-(methoxymethoxy)benzene (CAS 117570-31-7)
- 1-Fluoro-3-(methoxymethoxy)benzene (CAS 126940-10-1)
- 2-Fluoro-6-methoxy-4-methylphenol (CAS 127685-76-1)
- (4-Fluoro-3-methoxyphenyl)methanol (CAS 128495-45-4)
- 4-Fluoro-2-methoxy-5-methylphenol (CAS 1395035-39-8)
- 1-Fluoro-4-(methoxymethoxy)benzene (CAS 141362-06-3)
- 2-Fluoro-4-(1-hydroxyethyl)phenol (CAS 1517887-07-8)
Recommended Standards
- 2-Fluoro-3-methoxy-5-methylphenol (CAS 447462-92-2)
- 2-Fluoro-4-methoxybenzyl alcohol (CAS 405-09-4)
- 2-Fluoro-1,4-dimethoxybenzene (CAS 82830-49-7)
- 2-Fluoro-6-methoxybenzyl alcohol (CAS 253668-46-1)
- 3-amino-1-(2-aminophenyl)propan-1-one dihydrochloride (CAS 36681-58-0)
- 2-(2-Amino-5-fluorophenoxy)ethan-1-ol (CAS 1021022-66-1)
- 4-Cyclobutyl-1H-pyrazol-3-amine (CAS 1707602-39-8)
- 4-(3,5-Dimethoxyphenyl)butanal (CAS 591247-24-4)
- 5-(Furan-2-yl)cyclohexane-1,3-dione (CAS 1774-11-4)
- Carfilzomib Impurity 24 (CAS CATO-C4X-102224)
- 3-Methoxy-5-methyl-1H-pyrazol-4-amine (CAS 173682-30-9)
- N-(furan-3-ylmethyl)-6-methylpyrimidin-4-amine (CAS 883826-03-7)
- N-(2-Phenoxyethyl)-4-(trifluoromethyl)benzamide (CAS 879184-79-9)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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