Norepinephrine Impurity 34 HCl CAS 55-27-6
| CAS No. | 55-27-6 |
| Molecular Formula | C8H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 205.64 g/mol gives Norepinephrine Impurity 34 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Norepinephrine Impurity 34 HCl (CAS 55-27-6, C8H11NO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H11NO3HCl, Norepinephrine Impurity 34 HCl contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 205.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Norepinephrine Impurity 34 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11NO3 HCl |
| Molecular Weight | 205.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
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- 6-Bromo-2h-chromene-3-carbaldehyde (CAS 57543-37-0)
- 2-(2-Chloronicotinoyl)benzonitrile (CAS 884504-80-7)
- 2-Fluoropent-4-enoic acid (CAS 3885-23-2)
- 6-((3,5-Bis(trifluoromethyl)benzyl)thio)imidazo[2,1-b]thiazole-5-carbonitrile (CAS 400080-16-2)
- 1-(Prop-2-yn-1-yl)cyclohex-3-ene-1-carboxylic acid (CAS 1936088-43-5)
- 2-Cyano-N-(2-methoxyphenyl)-3-(p-tolyl)propanamide (CAS 505065-25-8)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
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