Naphazoline hydrochloride CAS 550-99-2
| CAS No. | 550-99-2 |
| Molecular Formula | C14H14N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Naphazoline hydrochloride (CAS 550-99-2), a certified reference material (molecular formula C14H14N2HCl, MW 246.74 g/mol) for analytical method development and quality control.
Naphazoline hydrochloride (C14H14N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14N2 HCl |
| Molecular Weight | 246.74 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Naphazoline Standards
- Naphazoline Impurity 2 (CAS 1019-21-2)
- Naphazoline EP Impurity C (CAS 132-75-2)
- Naphazoline Impurity 1 (CAS 17518-47-7)
- Naphazoline EP Impurity D (CAS 22126-67-6)
- Naphazoline EP Impurity A (CAS 36321-43-4)
- Naphazoline Impurity 6 (CAS 36660-46-5)
- Naphazoline Nitrate (CAS 5144-52-5)
- Naphazoline EP Impurity D Hydrochloride (CAS 6028-15-5)
Recommended Standards
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)propanamide (CAS 332101-02-7)
- 4-Benzyl-5-[(pyrrolidin-1-yl)methyl]-4h-1,2,4-triazole-3-thiol (CAS 790263-60-4)
- N-(3,5-bis(trifluoromethyl)phenyl)pivalamide (CAS 130721-86-7)
- 2-Chloro-5-hydroxy-4-methylbenzaldehyde (CAS 860753-80-6)
- 2-Bromo-4,6-difluorobenzyl chloride (CAS 1807071-32-4)
- Sitafloxacin Impurity 32 (CAS CATO-C4X-115532)
- Ethyl 4-(4-fluorophenyl)-1-hydroxy-2-oxopyrrolidine-3-carboxylate (CAS 866152-98-9)
- 3,3'-bis(Trifluoromethyl)benzophenone (CAS 1868-00-4)
- 1-Acetyl-3-bromoindole (CAS 66417-73-0)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
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