Methyl 6-fluorobenzo[b]thiophene-2-carboxylate CAS 550998-52-2
| CAS No. | 550998-52-2 |
| Molecular Formula | C10H7FO2S |
| Molecular Weight | 210.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 6-fluorobenzo[b]thiophene-2-carboxylate (C10H7FO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Methyl 6-fluorobenzo[b]thiophene-2-carboxylate (CAS 550998-52-2) is a high-purity analytical reference standard with the molecular formula C10H7FO2S and a molecular weight of 210.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 6-fluorobenzo[b]thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7FO2S |
| Molecular Weight | 210.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 5-fluorobenzo[b]thiophene-3-carboxylate (CAS 1187931-42-5)
- Methyl 4-fluorobenzo[b]thiophene-7-carboxylate (CAS 1393437-20-1)
- Methyl 5-fluorobenzo[b]thiophene-2-carboxylate (CAS 154630-32-7)
- Methyl 4-Fluorobenzo[b]thiophene-2-carboxylate (CAS 220180-55-2)
- Methyl 4-fluorobenzo[b]thiophene-5-carboxylate (CAS 313061-34-6)
- Methyl 7-fluorobenzo[b]thiophene-2-carboxylate (CAS 550998-54-4)
- 7-Fluorobenzo[b]thiophene-2-carbohydrazide (CAS 1048913-86-5)
- 4-Fluorobenzo[b]thiophene-2-carbohydrazide (CAS 1098351-44-0)
Recommended Standards
- Naphthalene-1-sulfonyl fluoride (CAS 317-55-5)
- Cyclopentyl(3,4-difluorophenyl)methanone (CAS 898791-96-3)
- 325-12-2 Naphthalene-2-sulfonyl fluoride DTXSID80496942 (CAS 325-12-2)
- Cyclopentyl 3,5-difluorophenyl ketone (CAS 898791-99-6)
- (6,8-Dimethyl-9H-1,3,4,9-tetraaza-fluoren-2-yl-sulfanyl)-acetic acid (CAS 482616-05-7)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-methoxy-5-methylpyridine (CAS 1806883-05-5)
- H-Lys-Val-OH (CAS 20556-11-0)
- 2-(Trifluoromethyl)quinolin-6-ol (CAS 143465-21-8)
- 3-(aminomethyl)-5-methyl-1,2-dihydropyridin-2-one hydrochloride (CAS 1803587-10-1)
- N-Tos-D/L Valine (CAS 32013-47-1)
- 2-Morpholinoacetaldehyde hydrochloride (CAS 1172495-88-3)
- Methyl 4-amino-3-bromo-5-iodobenzoate (CAS 1240113-86-3)
- 3-((Benzyloxy)methyl)cyclobutanecarboxylic acid (CAS 1363381-57-0)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com