2-(7-Chloro-1,8-naphthyridin-2-yl)isoindoline-1,3-dione CAS 55112-40-8
| CAS No. | 55112-40-8 |
| Molecular Formula | C16H8ClN3O2 |
| Molecular Weight | 309.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(7-Chloro-1,8-naphthyridin-2-yl)isoindoline-1,3-dione (C16H8ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(7-Chloro-1,8-naphthyridin-2-yl)isoindoline-1,3-dione (CAS 55112-40-8), molecular formula C16H8ClN3O2 and molecular weight 309.71 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(7-Chloro-1,8-naphthyridin-2-yl)isoindoline-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8ClN3O2 |
| Molecular Weight | 309.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- Methyl 1-benzyl-4-hydroxy-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-5-carboxylate (CAS 1428794-42-6)
- 1-Isopropyl-2-vinylbenzene (CAS 19789-33-4)
- (2E)-1,3-Bis(2,4-dichlorophenyl)prop-2-en-1-one (CAS 1335135-71-1)
- (S)-2-(Methoxymethyl)morpholine (CAS 157791-20-3)
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- 3-Hydroxy-4-(piperidin-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 66335-85-1)
- Pidotimod Impurity 31 (CAS 86028-91-3)
- 4-Phenyl-2,5-pyridinedicarboxylic acid (CAS 59195-28-7)
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