(E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one CAS 551920-80-0
| CAS No. | 551920-80-0 |
| Molecular Formula | C21H11Cl3F3NO2 |
| Molecular Weight | 472.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 472.67 g/mol gives (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one (CAS 551920-80-0), molecular formula C21H11Cl3F3NO2 and molecular weight 472.67 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one (C21H11Cl3F3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(2,6-dichlorophenyl)prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H11Cl3F3NO2 |
| Molecular Weight | 472.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (2E)-1-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one (CAS 672950-30-0)
- 3-Chloro-N-(2-chloro-6-methylphenyl)propanamide (CAS 39590-62-0)
- 10-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.0^{2,6}.0^{8,12}]tridec-4-ene-5-carboxylic acid (CAS 321998-80-5)
- 3-Benzyl-1-(3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-hydroxypyridin-2(1H)-one (CAS 551930-55-3)
- 2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetyl)-N-phenylhydrazine-1-carbothioamide (CAS 338979-13-8)
- N-(4-Chloro-3-methyl-1,2-oxazol-5-yl)-4-methoxy-N-(4-methoxybenzenesulfonyl)benzene-1-sulfonamide (CAS 478262-44-1)
- Methyl 5-((3-chloro-4-methylphenyl)carbamoyl)-2-(3-methoxybenzamido)-4-methylthiophene-3-carboxylate (CAS 332923-77-0)
- 2-{1-[3-chloro-4-(morpholin-4-yl)phenyl]-2,5-dimethyl-1H-pyrrol-3-yl}-N-(4-chlorophenyl)-2-oxoacetamide (CAS 860610-30-6)
Recommended Standards
- 1,1'-(Butane-1,4-diyl)bis(3-(3-isothiocyanatophenyl)thiourea) (CAS 711019-86-2)
- 4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-[4-[(2-hydroxy-1,1-dimethyl)ethyl]phenyl]butyne (CAS 1189696-09-0)
- 3-(4-(2,6-Diisopropylphenyl)-5-mercapto-4h-1,2,4-triazol-3-yl)-n,n-diethylbenzenesulfonamide (CAS 519150-25-5)
- Hecogenin Acetate (CAS 915-35-5)
- (E)-4-Methoxy-3-methyl-4-oxobut-2-enoic acid (CAS 39529-95-8)
- 5-(Cyclopropylmethyl)-2-methylphenol (CAS 1243353-88-9)
- 5-Iodo-6-methylpyrimidin-4(1H)-one (CAS 7752-74-1)
- 3-Methoxy-17α-methylestra-1,3,5(10)trien-17β-ol (CAS 15236-73-4)
- Tolylfluanid (CAS 731-27-1)
- 6-(3,4-Dimethoxybenzyl)-2-(4-methoxybenzylidene)-7H-thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione (CAS 638133-64-9)
- 4-Methyl-3-(pyridin-2-yl)-1h-pyrazol-5-amine (CAS 1312617-00-7)
- 4-(4-Nitro-1H-indol-3-yl)butan-2-one (CAS 885266-72-8)
- 2-((4-Fluorobenzyl)thio)aniline hydrochloride (CAS 1049757-38-1)
- Semaglutide impurity 29 (CAS 110990-08-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com