1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3,3-dimethylazetidin-2-one CAS 551930-63-3

Purity 97%+In StockPharmaceutical Standards
CAS No.551930-63-3
Molecular FormulaC11H11ClF3N3O
Molecular Weight293.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3,3-dimethylazetidin-2-one CAS 551930-63-3 chemical structure

Description

The occurrence of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3,3-dimethylazetidin-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3,3-dimethylazetidin-2-one (CAS 551930-63-3), a certified reference material (molecular formula C11H11ClF3N3O, MW 293.67 g/mol) for analytical method development and quality control.

The molecular framework of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3,3-dimethylazetidin-2-one (C11H11ClF3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H11ClF3N3O
Molecular Weight293.67 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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