(E)-1-(2-((4-chlorobenzyl)oxy)phenyl)-3-((4-(trifluoromethoxy)phenyl)amino)prop-2-en-1-one CAS 551931-16-9
| CAS No. | 551931-16-9 |
| Molecular Formula | C23H17ClF3NO3 |
| Molecular Weight | 447.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-1-(2-((4-chlorobenzyl)oxy)phenyl)-3-((4-(trifluoromethoxy)phenyl)amino)prop-2-en-1-one.
(E)-1-(2-((4-chlorobenzyl)oxy)phenyl)-3-((4-(trifluoromethoxy)phenyl)amino)prop-2-en-1-one (CAS 551931-16-9), molecular formula C23H17ClF3NO3 and molecular weight 447.83 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-1-(2-((4-chlorobenzyl)oxy)phenyl)-3-((4-(trifluoromethoxy)phenyl)amino)prop-2-en-1-one (C23H17ClF3NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H17ClF3NO3 |
| Molecular Weight | 447.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
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