5-Fluoro-2-(4-methylphenoxy)aniline CAS 55321-60-3
| CAS No. | 55321-60-3 |
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.24 g/mol gives 5-Fluoro-2-(4-methylphenoxy)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Fluoro-2-(4-methylphenoxy)aniline (CAS 55321-60-3), molecular formula C13H12FNO and molecular weight 217.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Fluoro-2-(4-methylphenoxy)aniline (C13H12FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-2-(4-methylphenoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-amine (CAS 1048915-78-1)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-4-amine (CAS 1182804-44-9)
- 2'-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-amine (CAS 1184082-67-4)
- 4'-Fluoro-4-methoxy-[1,1'-biphenyl]-3-amine (CAS 1214367-37-9)
- 4-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-amine (CAS 1225961-50-1)
- 6-Fluoro-N-((3-methylpyridin-2-yl)methyl)pyridin-2-amine (CAS 1333514-25-2)
- (4-Fluoro-2-methylphenyl)(pyridin-2-yl)methanol (CAS 1339194-11-4)
- (4-Fluoro-3-methylphenyl)(pyridin-2-yl)methanol (CAS 1340029-13-1)
Recommended Standards
- 5-Fluoro-2-(2-methylphenoxy)aniline (CAS 946729-40-4)
- 5-Fluoro-2-(m-tolyloxy)aniline (CAS 937596-33-3)
- 5-Amino-2-ethoxybenzenesulfonic acid (CAS 6375-02-6)
- 5-Fluoro-3-(3-oxycyclopentyl)indole (CAS 675831-63-7)
- Ethyl 2-amino-2-(pyridin-2-yl)acetate hydrochloride (CAS 1910766-97-0)
- 3-(2-Fluorophenyl)-1-(1,2,3,4-tetrahydroisoquinolin-5-yl)urea (CAS 1157922-38-7)
- Methyl 5-(chlorosulfonyl)-2-iodo-3-methylbenzoate (CAS 1154155-39-1)
- 3-(2-Aminoethyl)-2-methyl-1H-indole-5-carbonitrile hydrochloride (CAS 1049737-40-7)
- Ebeiedinone (CAS 25650-68-4)
- (2,6-Difluorophenyl)(4-methylpyridin-2-yl)methanone (CAS 1187170-46-2)
- 2-Bromo-4-(hydroxymethyl)benzonitrile (CAS 90110-97-7)
- 1-(4-Hydroxy-2,6-dimethoxyphenyl)ethanone (CAS 13246-14-5)
- 9-Amino-9-oxononanoic acid (CAS 61798-00-3)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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