tert-Butyl 4-(2-bromophenyl)-4-hydroxypiperidine-1-carboxylate CAS 553631-01-9

Purity 97%+In StockPharmaceutical Standards
CAS No.553631-01-9
Molecular FormulaC16H22BrNO3
Molecular Weight356.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 4-(2-bromophenyl)-4-hydroxypiperidine-1-carboxylate CAS 553631-01-9 chemical structure

Description

The molecular framework of tert-Butyl 4-(2-bromophenyl)-4-hydroxypiperidine-1-carboxylate (C16H22BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

tert-Butyl 4-(2-bromophenyl)-4-hydroxypiperidine-1-carboxylate (CAS 553631-01-9), molecular formula C16H22BrNO3 and molecular weight 356.25 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures tert-Butyl 4-(2-bromophenyl)-4-hydroxypiperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H22BrNO3
Molecular Weight356.25 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentBr-containing
Nitrogen Atoms1

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