2-(Methylamino)-2-phenylacetonitrile hydrochloride CAS 5537-52-0
| CAS No. | 5537-52-0 |
| Molecular Formula | C9H10N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Methylamino)-2-phenylacetonitrile hydrochloride (C9H10N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(Methylamino)-2-phenylacetonitrile hydrochloride (CAS 5537-52-0) is a high-purity analytical reference standard with the molecular formula C9H10N2HCl and a molecular weight of 182.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Methylamino)-2-phenylacetonitrile hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10N2 HCl |
| Molecular Weight | 182.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methylamino Standards
- 4-(Methylamino)phenyl furan-2-carboxylate (CAS 100063-33-0)
- 2-(methylamino)-6,7-dihydro-3H-purin-6-one (CAS 10030-78-1)
- 6-(Methylamino)pyridine-3-boronic Acid Pinacol Ester (CAS 1005009-98-2)
- 2-(Methylamino)cyclopentan-1-ol (CAS 100524-01-4)
- 2-(Methylamino)ethane-1-thiol (CAS 10061-40-2)
- 1-(2-(Methylamino)-2-oxoethyl)-1H-pyrazole-3-carboxylic acid (CAS 1006463-30-4)
- Ethyl 4-((methylamino)methyl)benzoate hydrochloride (CAS 1007870-76-9)
- 2-methyl-2-(methylamino)-1-phenyl-propan-1-ol (CAS 10079-55-7)
Recommended Standards
- Potassium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate (CAS 26763-19-9)
- 3-Methyl-9-phenyl-9h-carbazole (CAS 1202362-88-6)
- 2-cyclopropyl-5-methylbenzoic acid (CAS 1525520-64-2)
- 1-[(1-Ethyl-5-methyl-1H-pyrazol-4-yl)methyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 1172394-80-7)
- 2-(methoxymethyl)-2-methyloxirane (CAS 37459-10-2)
- Carbamazepine 10,11-Epoxide-d2 (Major) (CAS 1185025-41-5)
- 2-(3-AMINOPROPYL)IMIDAZOLE 2HCL (CAS 33544-86-4)
- (1R,3r)-1-bromo-3-(tert-butoxy)cyclobutane (CAS 1909287-94-0)
- (S)-Lisofylline (CAS 100324-80-9)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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