O-Acetylsalicyloyl Chloride CAS 5538-51-2
| CAS No. | 5538-51-2 |
| Molecular Formula | C9H7ClO3 |
| Molecular Weight | 198.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, O-Acetylsalicyloyl Chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
O-Acetylsalicyloyl Chloride (CAS 5538-51-2), molecular formula C9H7ClO3 and molecular weight 198.60 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures O-Acetylsalicyloyl Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7ClO3 |
| Molecular Weight | 198.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Recommended Standards
- 8-Chloro-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (CAS 851398-61-3)
- Benzyl 2-chloro-2-oxoacetate (CAS 35249-73-1)
- 7-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 26018-45-1)
- Cefamandole Impurity 10 (CAS 29169-64-0)
- Acetylsalicylic Acid Acyl-D-Glucuronide (CAS 24719-72-0)
- 2-[1-(1-methylcyclopropyl)sulfonylazetidin-3-ylidene]acetonitrile (CAS 1187594-27-9)
- N-(4-cyclohexylphenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)acetamide (CAS 329071-92-3)
- 1-(3,4-Dimethoxyphenyl)cyclobutanamine (CAS 1017467-28-5)
- Tetrahydro-1H-cyclopenta[c]pyridine-3,6(2H,4H)-dione (CAS 1822614-57-2)
- Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate (CAS 880090-88-0)
- 2-(Naphthalen-1-ylsulfinyl)benzoic acid (CAS 131073-64-8)
- 4-(4-(Trifluoromethoxy)phenyl)thiazol-2(3h)-imine (CAS 436151-95-0)
- 2-(3,3-Difluoroazetidin-1-yl)-5-(trifluoromethyl)pyridine 1707581-24-5 (CAS 1707581-24-5)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com