5-(2-Chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide CAS 5541-92-4
| CAS No. | 5541-92-4 |
| Molecular Formula | C8H6ClN3O2S2 |
| Molecular Weight | 275.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2-Chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide.
CATO supplies 5-(2-Chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide (CAS 5541-92-4), a certified reference material (molecular formula C8H6ClN3O2S2, MW 275.74 g/mol) for analytical method development and quality control.
The molecular framework of 5-(2-Chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide (C8H6ClN3O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(2-Chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN3O2S2 |
| Molecular Weight | 275.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 6-Chloro-N-(1,3-thiazol-2-yl)pyridine-3-sulfonamide (CAS 622804-28-8)
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- 5-Carboxy-2-fluorophenylboronic Acid (CAS 874219-59-7)
- 1-Ethenyl-4-oxo-cyclohexanecarboxylic Acid (CAS 1082207-50-8)
- 2-amino-N-(naphthalen-1-yl)acetamide hydrochloride (CAS 1240526-11-7)
- Methyl Indoline-4-carboxylate (CAS 155135-61-8)
- 1-Methylpyrrole-2-carboxamide (CAS 64230-41-7)
- Benserazide Impurity 44 (CAS CATO-C4X-142744)
- 97764-44-8 tert-Butyl(phenyl)phosphane--boron (1/1) DTXSID10586906 (CAS 97764-44-8)
- 4-Cyanophenyl chloroformate (CAS 64459-25-2)
- N-[(1S)-1-{[(1S)-5-amino-1-{[({[(5S)-5-ethyl-5-hydroxy-6,10-dioxo-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.0²,¹¹.0⁴,⁹.0¹⁵,²³.0¹⁷,²¹]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaen-14-yl]methyl}carbamoyl)methyl]carbamoyl}pentyl]carbamoyl}-2-methylpropyl]-1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12-tetraoxapentadecan-15-amide (CAS 2378428-19-2)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
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